Genes carry the biological information we inherit from our parents. They affect the way our bodies grow, work and look. Changes (mutations) in certain genes can increase the risk of bowel cancer in family members who inherit the genetic change. However, only a small number of bowel cancers are thought to be due to an inherited altered gene (genetic mutation) running in the family.
How does my family history affect my risk of developing bowel cancer?
It is only likely that a genetic mutation that can increase your bowel cancer risk is present in your family, if you have:
- at least two close relatives on the same side of the family who developed bowel cancer
- one close relative who got bowel cancer at a young age (under 45)
- cases of bowel and womb cancer on the same side of your family.
Your close relatives are your parents, children, brothers and sisters. They are also sometimes called your first degree relatives.
If your family is like this, and you are worried about developing bowel cancer yourself, you might want to talk to your GP. They will ask you questions about your family history. If your GP thinks there’s a chance that you might have an increased risk of developing bowel cancer because of your family history, they will refer you to a genetic counsellor, family cancer clinic or a cancer specialist.
Everyone in England, when they reach 60 (50 in Scotland), will be invited to join the NHS’s new Bowel Cancer Screening Programme, and offered a faecal occult blood (FOB) test every two years. The FOB test looks for hidden traces of blood in faeces (bowel motions).
People who seem to be at a higher than average risk of developing bowel cancer may be offered regular screening using a colonoscopy, where a long flexible tube is inserted into the back passage to look at the inside of the bowel. This can help to detect bowel cancer early.
If you only have one elderly relative who has developed bowel cancer, or one case of bowel cancer on each side of your family, this does not significantly increase your risk. If you had one of the bowel cancer genes in your family, then it is likely that more than one relative on the same side of the family would have developed bowel cancer.
If you are still worried
It can be a normal reaction to severe illness in the family, or to bereavement, to feel more vulnerable to the same disease. If you can’t stop worrying, you may find it helpful to see a counsellor, who can help you get things back into perspective. You can ask your GP, or call our nurses for details of a local service. You could also call the Cancer Counselling Trust to speak to a counsellor.
Mind, the mental health charity, has published a leaflet called 'How to Stop Worrying'.