The information in the cancer of the large bowel information centre is based on the Cancerbackup booklet, Understanding cancer of the large bowel, which was produced in accordance with the following sources and guidelines:

• Improving Outcomes in Colorectal Cancer: The Manual Update. National Institute for Health and Clinical Excellence (NICE), June 2004.
• Computerised tomographic colonoscopy (virtual colonoscopy) – guidance. NICE, June 2005.
• Full Guidance on the use of Irinotecan, Oxaliplatin and Raltitrexed for the Treatment of Advanced Colorectal cancer. NICE, June 2003.
• Colorectal Cancer – Laparascopic Surgery (No 17). NICE, November 2003.
• Full Guidance on the use of Capecitabine and Tegafur with Uracil for Metastatic Colorectal Cancer. NICE, May 2003.
• Management of Colorectal Cancer: A National Clinical Guideline. Scottish Intercollegiate Guidelines Network (SIGN), March 2003.
• Bevacizumab and Cetuximab for the Treatment of Metastatic Colorectal Cancer. NICE, January 2007.
• Capecitabine and Oxaliplatin in the Adjuvant Treatment of Stage III (Dukes’ C) Colon Cancer. NICE, April 2006.

Guidelines are constantly being updated and those noted above may have been revised since the booklet was produced. You can access up-to-date guidelines in the health professionals section of the website.