Cancerbackup: Dealing with symptoms

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Dealing with the symptoms of secondary liver cancer

Treating secondary cancer in the liver with any of the treatments in the previous sections can help to ease any symptoms you may have. If it is not possible to use these treatments, or if they are not effective, there are several other ways of helping you cope with any symptoms. This symptom control treatment is known as palliative therapy or supportive care.


Tiredness

Many people with liver cancer find that they feel tired and don’t have the energy to do everyday activities.


Loss of appetite

Some people may lose interest in food. Medicines such as steroids or a hormone called megestrol acetate (Megace®) can be prescribed by your doctor to increase your appetite.


Feeling sick (nausea)

Liver cancer can make you feel sick by changing the chemical balance in the blood. This can often be effectively relieved by anti-sickness tablets (anti-emetics). There are several different types of anti-emetics available and your doctor will find the one that suits you best. Steroids are often used, as these can help to relieve sickness and make you feel more energetic, as well as improving your appetite.


Pain

Secondary cancer of the liver can make the liver grow larger. The enlarged liver stretches the capsule that surrounds it, which causes pain.

Chemotherapy may shrink the enlarged liver and this can help relieve the pain, but there are also several effective types of painkillers available that your doctor can prescribe.

Strong painkillers can cause constipation, so it is important to try to have a diet high in fibre and drink plenty of fluids. Your doctor can prescribe a laxative with your painkillers to prevent constipation.

Our section, controlling cancer pain, gives more information about painkilling drugs and other ways of relieving pain.

Steroids can also help to shrink the enlarged liver. They are usually given as a course of treatment lasting some weeks or months.

Radiotherapy may also be used to relieve your pain. This treatment may cause side effects, depending on the strength of the dose and the length of your treatment.


Ascites

Ascites is the name given to a build-up of fluid in the abdomen, which can make you feel bloated and uncomfortable. You may have less of an appetite and you might also feel breathless as the swelling can prevent your lungs from fully expanding as you breathe. Ascites can sometimes be reduced by taking water tablets (also called diuretics) which your doctor can prescribe. These are drugs that encourage the body to get rid of excess fluid as urine, rather than allowing it to collect in the body.

Ascites can also be relieved by inserting a small tube into the abdomen to drain off the excess fluid. This is done in hospital, with a local anaesthetic, and can be repeated when necessary. Sometimes this procedure can be done at home by your doctor.


Jaundice

Sometimes the bile duct – the tube that drains bile out of the liver and into the intestine (see the diagram of the liver) – can become blocked by the cancer. If this happens, bile builds up in the liver and flows back into the blood. It makes the skin turn yellow and feel itchy. This is called jaundice. The itching may sometimes be relieved by antihistamine tablets or other drugs which your doctor can prescribe.

Depending on where the blockage has occurred, the jaundice can sometimes be relieved by inserting a narrow tube (stent) into the bile duct to keep it open. This allows the bile to flow normally into the small intestine.


Extremes in body temperature

As the liver is the major heat-producing organ of the body, people with liver cancer sometimes find that they have changes in body temperature (either feeling too hot and sweating, or feeling cold and shivering). Speak to your doctor if you have these changes, as there may be medicines which can help.


Hiccups

Hiccups may occur if the liver is pressing on the nerve that leads to the diaphragm (the muscle layer separating the chest from the abdomen). Medicines which can sometimes reduce or stop hiccups are available.


Itching

If the itching is due to jaundice, having frequent showers can wash off the bile salts and help relieve the itching. Try to avoid soaps which dry the skin and may increase itching. You may find moisturising lotions helpful. Some medicines can also help to relieve itching. Your doctor can prescribe these for you.


Content last reviewed: 01 January 2008
Page last modified: 08 May 2008

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