Cancerbackup: Q-1135

Skip the page content navigation if you do not require links to content sections within this page.

Page Content Navigation

Skip the main banner if you do not want to read it as the next section.


Page Banner

Want to speak to a specialist cancer nurse? Call free on 0808 800 1234



The best cancer information for everyone.
Cancerbackup has merged with Macmillan. Together we can provide a wealth of high quality information about cancer.


Skip the main content if you do not want to read it as the next section.


I have prostate cancer. A friend has told they have read about a vaccine treatment for the condition. Can you tell me more about this?

At the present time the development of vaccines for prostate cancer is at the research stage. Some limited clinical trials of vaccines are under way but these are mainly looking at the safety of the vaccines and finding out whether they have any effect. So for the moment vaccine therapy is certainly not a routine part of the treatment of prostate cancer.

The cells in the prostate gland produce a protein called prostate specific antigen (PSA). When prostate cells become cancerous they usually produce larger amounts of PSA than normal (causing an increase of the PSA level in the blood which can be measured by a simple blood test). There are also changes on the outer lining or cell membrane of cancerous prostate cells where PSA forms as something called prostate-specific membrane antigen.

Most of the vaccines under development for prostate cancer are targeted against prostate specific membrane antigen. The hope is that these vaccines will boost the patient's own immune system so that it recognises the cells carrying the antigen and destroys them.

For the moment, however, this remains a hope rather than a reality and the treatment is still at an early and experimental stage and there is no sure evidence that it will work.


Content last reviewed: 27 July 2005
Page last modified: 28 June 2007

Get support

Look for other people in the same situation on our What Now? community - read their blogs or talk to them in our chat rooms.

Find out about other ways to get support on the main Macmillan website.

Related information