Last reviewed: March 2007
For general information about Cancerbackup's Discussion topics please see the introductory page.
Cancerbackup is a national voluntary organisation providing information, support and a range of publications to people with cancer, their families and friends and health professionals involved in their care. Cancerbackup’s Clinical Advisory Board advises its cancer information service on issues of controversy and concern.
This report is a review of the risks and benefits of using HRT (Hormone Replacement Therapy) following menopause.
During menopause, loss of oestradiol production leads to many changes that may have adverse effects on a woman’s quality of life. These changes include: vasomotor symptoms (hot flushes); increased risk of osteoporosis leading to fractures; vaginal and urinary symptoms; problems with memory and loss of self-esteem.
HRT can improve certain menopausal symptoms such as hot flushes and vaginal dryness, and can reduce the risk of fractures from osteoporosis. But there has been concern for many years about the possible adverse effects of HRT use on the health of menopausal women. One of the anxieties women have is the link between HRT use and breast cancer risk. There have now been several studies published regarding this, including the Million Women Study (2) and the WHI Estrogen Alone Study (35).