Cancerbackup: Vaccinations & immunisations

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Travel vaccinations and immunisations for people with cancer

Immunisations are used to stimulate your body’s natural defences, to try and reduce the chance of you catching certain infections. If you have had particular types of cancer, or particular cancer treatments, you may not be able to have some of the vaccinations that you need in order to travel to some parts of the world. This may influence your choice of holiday destination.


Live vaccines

Live attenuated vaccines use tiny amounts of the live virus or bacteria, which has been changed (attenuated)  so that it does not cause the infection. They stimulate the immune system to develop protective white blood cells (antibodies) to protect against the infection.

If you have a weakened immune system you should not have live vaccines. Your immune system may be weakened if you have had chemotherapy or total body radiotherapy during the previous 6 months, or if you have had high-dose chemotherapy with a stem cell transplant within the last 6 months. Steroid therapy can weaken your immunity for 3 months.

Live vaccines include:

  • measles
  • mumps
  • rubella
  • MMR
  • poliomyelitis liquid
  • liquid typhoid
  • BCG
  • yellow fever.

If you have a weakened immunity, your family and friends should also avoid having liquid typhoid and liquid polio vaccinations.

Some people may need to avoid live vaccines for the rest of their life; for example, if they have had a lymphoma or leukaemia, or if their cancer is related to HIV infection. You can check with your GP or cancer specialist whether it is safe for you to have vaccinations.


Inactivated vaccines

Although inactivated vaccines are not dangerous, and are safe to give after cancer treatment, they may be less effective in people who have a weakened immunity.

Inactivated vaccines include:

  • diphtheria toxoid
  • tetanus toxoid
  • pertussis (whooping cough)
  • poliomyelitis injection
  • haemophilus influenza B (Hib)
  • influenza
  • hepatitis A
  • typhoid injection
  • meningococcal meningitis
  • Japanese encephalitis
  • tick-bourne encephalitis
  • hepatitis B
  • rabies
  • cholera

Re-vaccination

If you have had high-dose chemotherapy and a stem cell transplant, you may have lost immunity to diseases that you have previously been vaccinated against. You may need to be re-vaccinated 6 months after your treatment.

The type of vaccinations you may need to have for your holiday will depend on where you are going. Your doctor can give you advice on what is best for you.

If you have lymphoedema in an arm, it is important to make sure that vaccinations are given in the unaffected arm.


Splenectomy

If you have had your spleen removed (splenectomy), or if you are about to have this operation, you will have a lower resistance to particular types of infection and should be vaccinated against pneumococcus haemophilus influenza type b and meningococcus, preferably before the splenectomy.

Before travelling, your doctor should give you a supply of antibiotics and tell you when you should take them.

Malaria can be especially severe if you have had your spleen removed, and you may want to avoid travelling to countries where malaria is a problem. If you do wish to travel to these countries, it is essential to have appropriate protection against malaria. However, no medicinal protection is 100% effective, and bed nets and repellents are important to make sure that you do not get malaria.

The Medical Advisory Service for Travellers Abroad (MASTA) can give information on vaccination.


Content last reviewed: 01 August 2006
Page last modified: 06 November 2006

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