Cancerbackup: Q-588

Skip the page content navigation if you do not require links to content sections within this page.

Page Content Navigation

Skip the main banner if you do not want to read it as the next section.


Page Banner

Want to speak to a specialist cancer nurse? Call free on 0808 800 1234



The best cancer information for everyone.
Cancerbackup has merged with Macmillan. Together we can provide a wealth of high quality information about cancer.


Skip the main content if you do not want to read it as the next section.


Does chemotherapy affect fertility? My boyfriend, aged 25, is about to have chemotherapy for Hodgkin lymphoma. We are planning to get married next year and would like to have children in the future.

Yes, chemotherapy can affect a man's fertility (ability to father a child). Some chemotherapy drugs are more likely to affect fertility than others. The dose of the drugs and the length of time they are given over are also factors. It is probably a good idea for you to discuss this as a couple with your boyfriend’s cancer specialist, who will know the drugs he is going to have. The newer combinations of chemotherapy drugs used to treat Hodgkin lymphoma, such as ABVD, are less likely to cause infertility than those used previously.

The effect on sperm production may be temporary or permanent. Following treatment it may take several years for fertility to recover. Some men with Hodgkin lymphoma have reduced fertility before starting any treatment for reasons that are unknown.

Couples are advised to avoid getting pregnant during chemotherapy, as the drugs may harm the developing foetus, and for a few months afterwards. Condoms should be used during sex for the first 48 hours after chemotherapy to protect partners from any of the drug that may be present in semen.

As it is not possible to predict whether a man's fertility will be affected, or if it will return after treatment, many men choose to store sperm before they start. The cancer centre usually meets the costs of sperm storage.

If you are both concerned about your boyfriend's future fertility it's important to to discuss this with his doctors, before chemotherapy starts. They will be able to advise him on whether he needs to consider sperm storage, and if necessary refer him to a fertility clinic.


Content last reviewed: 01 November 2004
Page last modified: 05 June 2006

Get support

Look for other people in the same situation on our What Now? community - read their blogs or talk to them in our chat rooms.

Find out about other ways to get support on the main Macmillan website.